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Bioactive Nanofibres for Wound Healing Applications
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Bioactive Nanofibres for Wound Healing Applications

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ABSTRACT


Electrospun nanofibres have become an exciting area in textile product development, due to their unique properties such as high surface area and porosity. Indeed, many studies on nanofibres have demonstrated their feasibility in various applications. For example, nanofibre scaffolds were shown to be promoters for tissue cell adhesion and encapsulators for drugs. In the past decade, numerous studies revealed the areas in which nanofibres can be useful, and capability for scaling-up nanofibre production, which established a starting step in the development of a new generation of textile products. However, many challenges faced today are complicated in nature and require a multidimensional approach to solve, necessitating multifunctional products. This review explored recent efforts in developing a new class of active textiles for wound care. The wound care sector is one of the most advanced in the medical industry, with a massive global demand from patients suffering from wounds, burns, and diseases such as diabetes. Ensuring satisfactory wound healing is often difficult due to the dynamic nature of the skin, requiring fulfilment of multiple objectives at different stages of the healing process. We demonstrated that by controlling how wound dressing release therapeutic agents, its mechanical responses to the wound and in aqueous environment, a wound dressing that can interact with different wounds can be developed.


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This article was originally published in the New Cloth Market magazine, May, 2012.


About the Authors:


Victor Leung, Heejae Yang, & Frank Ko are associated with the University of British Columbia, Vancouver, BC V6T 1Z4, Canada


Ryan Hartwell & Aziz Ghahary are associated with the Vancouver General Hospital, Vancouver, BC V5Z 1 M9, Canada

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